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\n \n 'Basal-like' breast cancer does not originate from basal stem cells \n

\n New research uncovers a case of mistaken identity that may have a significant impact on future breast cancer prevention and treatment strategies. The study suggests that despite their \"stem cell-like\" characteristics, most aggressive breast tumors are not derived from normal mammary gland stem cells.

\n 09/06/10 5:00 am

\n \n 'Co-conspirator' cells could hold key to melanoma prediction, prevention \n

\n New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling \"co-conspirators\" in the genesis of melanoma, in findings that could someday hold the key to predicting, preventing and stopping this hard-to-treat cancer before it spreads.

\n 08/31/10 5:00 am

\n \n Advanced melanoma: New targeted therapy successful in more than 80 percent of patients \n

\n Use of an experimental targeted drug to treat metastatic melanoma tumors with a specific genetic signature was successful in more than 80 percent of patients in a phase 1 clinical trial. Results of the trial of PLX4032, an inhibitor of a protein called BRAF that is overactive in more than half of all melanomas, appear in a new study.

\n 08/26/10 8:00 am

\n \n Lung stem cells vital to lung repair associated with poor cancer prognosis when found in tumor \n

\n Adult stem cells that are vital for airway repair in the lung but that persist in areas where pre-cancerous lesions are found are associated with a poor prognosis in patients who develop cancer, even those with early stage disease, researchers have found.

\n 08/17/10 2:00 pm

\n \n Advance toward earlier detection of melanoma \n

\n Scientists are now able to image subcutaneous melanoma tumors with startling clarity. The new imaging technique relies on sound rather than light because sound is less strongly scattered by tissues. In addition, the tumors are preloaded with a nanoparticle contrast agent that latches onto proteins that stud the surface of the cancerous cells.

\n 08/11/10 2:00 pm

\n \n The evolution of melanoma diagnosis: 25 years beyond the ABCDs \n

\n Twenty-five years after publishing the mnemonic \"ABCD\" to facilitate the early diagnosis of melanoma, the group who came up with that moniker says early detection remains a key factor in lowering mortality from malignant melanoma.

\n 07/28/10 9:00 pm

\n \n Melanoma rates among minorities in Florida differ from national trends \n

\n Racial and ethnic trends in the skin cancer melanoma appear different in Florida than from national estimates, with higher incidence rates among Hispanic men and non-Hispanic black women but lower rates among Hispanic women, according to a new study.

\n 07/18/10 9:00 pm

\n \n Scientists create army of tumor-fighting immune cells and watch as they attack cancer \n

\n Researchers created a large, well-armed battalion of tumor-seeking immune system cells and watched, in real time using positron emission tomography (PET), as the special forces traveled throughout the body to locate and attack dangerous melanomas.

\n 07/13/10 2:00 am

\n \n New way to slow the growth of malignant melanoma \n

\n New research has shown that the growth of melanoma, one of the most deadly forms of skin cancer, can be slowed when a little known gene called microRNA 193b is added.

\n 07/09/10 2:00 am

\n \n UVA radiation damages DNA in human melanocyte skin cells and can lead to melanoma \n

\n A new study has found that UVA radiation damages the DNA in human melanocyte cells, causing mutations that can lead to melanoma. Melanocytes, which contain a substance called melanin that darkens the skin to protect it from the ultraviolet rays of the sun, are more vulnerable to UVA radiation than normal skin cells because they are unable to repair themselves as efficiently.

\n 07/02/10 2:00 am

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